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-Structure paper
Title | Fragment-Based Discovery of Bromodomain Inhibitors Part 2: Optimization of Phenylisoxazole Sulfonamides. |
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Journal, issue, pages | J. Med. Chem., Vol. 55, Page 587-, Year 2012 |
Publish date | Nov 26, 2011 (structure data deposition date) |
Authors | Bamborough, P. / Diallo, H. / Goodacre, J.D. / Gordon, L. / Lewis, A. / Seal, J.T. / Wilson, D.M. / Woodrow, M.D. / Chung, C.W. |
External links | J. Med. Chem. / PubMed:22136469 |
Methods | X-ray diffraction |
Resolution | 1.78 - 2.06 Å |
Structure data | PDB-4a9m: PDB-4a9n: PDB-4a9o: PDB-4alh: |
Chemicals | ChemComp-P9M: ChemComp-SO4: ChemComp-HOH: ChemComp-EDO: ChemComp-A9N: ChemComp-DMS: ChemComp-A9O: ChemComp-A9P: |
Source |
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Keywords | SIGNALING PROTEIN / INHIBITOR / HISTONE / EPIGENETIC READER / SIGNALING PROTEIN/INHIBITOR / SIGNALING PROTEIN-INHIBITOR COMPLEX |