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-Structure paper
Title | 2-Thioxanthines are Mechanism-Based Inactivators of Myeloperoxidase that Block Oxidative Stress During Inflammation. |
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Journal, issue, pages | J. Biol. Chem., Vol. 286, Page 37578-, Year 2011 |
Publish date | Jun 21, 2011 (structure data deposition date) |
Authors | Tiden, A.K. / Sjogren, T. / Svensson, M. / Bernlind, A. / Senthilmohan, R. / Auchere, F. / Norman, H. / Markgren, P.O. / Gustavsson, S. / Schmidt, S. ...Tiden, A.K. / Sjogren, T. / Svensson, M. / Bernlind, A. / Senthilmohan, R. / Auchere, F. / Norman, H. / Markgren, P.O. / Gustavsson, S. / Schmidt, S. / Lundquist, S. / Forbes, L.V. / Magon, N.J. / Paton, L.N. / Jameson, G.N. / Eriksson, H. / Kettle, A.J. |
External links | J. Biol. Chem. / PubMed:21880720 |
Methods | X-ray diffraction |
Resolution | 2.3 - 2.6 Å |
Structure data | PDB-3zs0: PDB-3zs1: |
Chemicals | ChemComp-SO4: ChemComp-ZS0: ChemComp-HEM: ChemComp-NAG: ChemComp-CA: ChemComp-CL: ChemComp-ACT: ChemComp-HOH: ChemComp-PVW: |
Source |
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Keywords | OXIDOREDUCTASE / ENZYME INACTIVATION / INFLAMMATION / NEUTROPHIL / REACTIVE OXYGEN SPECIES (ROS) / HYPOCHLOROUS ACID |