+Search query
-Structure paper
Title | Structural, Kinetic, and Pharmacodynamic Mechanisms of D-Amino Acid Oxidase Inhibition by Small Molecules. |
---|---|
Journal, issue, pages | J. Med. Chem., Vol. 56, Page 3710-, Year 2013 |
Publish date | Feb 15, 2013 (structure data deposition date) |
Authors | Hopkins, S.C. / Heffernan, M.L.R. / Saraswat, L.D. / Bowen, C.A. / Melnick, L. / Hardy, L.W. / Orsini, M.A. / Allen, M.S. / Koch, P. / Spear, K.L. ...Hopkins, S.C. / Heffernan, M.L.R. / Saraswat, L.D. / Bowen, C.A. / Melnick, L. / Hardy, L.W. / Orsini, M.A. / Allen, M.S. / Koch, P. / Spear, K.L. / Foglesong, R.J. / Soukri, M. / Chytil, M. / Fang, Q.K. / Jones, S.W. / Varney, M.A. / Panatier, A. / Oliet, S.H.R. / Pollegioni, L. / Piubelli, L. / Molla, G. / Nardini, M. / Large, T.H. |
External links | J. Med. Chem. / PubMed:23631755 |
Methods | X-ray diffraction |
Resolution | 1.9 - 2.75 Å |
Structure data | PDB-3znn: PDB-3zno: PDB-3znp: PDB-3znq: |
Chemicals | ChemComp-FAD: ChemComp-4WL: ChemComp-GOL: ChemComp-HOH: ChemComp-SE5: ChemComp-SE2: ChemComp-SS8: |
Source |
|
Keywords | OXIDOREDUCTASE / FLAVOOXIDASE / NEUROTRANSMISSION / SMALL MOLECULE INHIBITION |