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TitleActivity-Based Probes for Rhomboid Proteases Discovered in a Mass Spectrometry-Based Assay.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 110, Page 2472-, Year 2013
Publish dateDec 4, 2012 (structure data deposition date)
AuthorsVosyka, O. / Vinothkumar, K.R. / Wolf, E.V. / Brouwer, A.J. / Liskamp, R.M.J. / Verhelst, S.H.L.
External linksProc. Natl. Acad. Sci. USA / PubMed:23359682
MethodsX-ray diffraction
Resolution2.2 Å
Structure data

PDB-3zeb:
A complex of GlpG with isocoumarin inhibitor covalently bonded to serine 201 and histidine 150
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-SV1:
2-phenylethyl 2-(4-azanyl-2-methanoyl-phenyl)ethanoate

ChemComp-CL:
Unknown entry

ChemComp-BNG:
nonyl beta-D-glucopyranoside / detergent*YM

ChemComp-HOH:
WATER

Source
  • escherichia coli (E. coli)
KeywordsHYDROLASE / INTRA-MEMBRANE PROTEASE / SERINE PROTEASE / ACYL ENZYME

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