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-Structure paper
Title | Novel benzimidazole derivatives as phosphodiesterase 10A (PDE10A) inhibitors with improved metabolic stability. |
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Journal, issue, pages | Bioorg. Med. Chem., Vol. 22, Page 3515-3526, Year 2014 |
Publish date | Mar 4, 2014 (structure data deposition date) |
Authors | Chino, A. / Masuda, N. / Amano, Y. / Honbou, K. / Mihara, T. / Yamazaki, M. / Tomishima, M. |
External links | Bioorg. Med. Chem. / PubMed:24837154 |
Methods | X-ray diffraction |
Resolution | 2.6 - 2.99 Å |
Structure data | PDB-3ws8: PDB-3ws9: |
Chemicals | ChemComp-ZN: ChemComp-MG: ChemComp-X4C: ChemComp-HOH: ChemComp-X4D: |
Source |
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Keywords | HYDROLASE/HYDROLASE INHIBITOR / phosphodiesterase / HYDROLASE-HYDROLASE INHIBITOR complex |