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Title | Toxicity Modulation, Resistance Enzyme Evasion, and A-Site X-ray Structure of Broad-Spectrum Antibacterial Neomycin Analogs |
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Journal, issue, pages | Acs Chem. Biol., Vol. 9, Page 2067-2073, Year 2014 |
Publish date | Feb 27, 2014 (structure data deposition date) |
![]() | Maianti, J.P. / Kanazawa, H. / Dozzo, P. / Matias, R.D. / Feeney, L.A. / Armstrong, E.S. / Hildebrandt, D.J. / Kane, T.R. / Gliedt, M.J. / Goldblum, A.A. ...Maianti, J.P. / Kanazawa, H. / Dozzo, P. / Matias, R.D. / Feeney, L.A. / Armstrong, E.S. / Hildebrandt, D.J. / Kane, T.R. / Gliedt, M.J. / Goldblum, A.A. / Linsell, M.S. / Aggen, J.B. / Kondo, J. / Hanessian, S. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.3 Å |
Structure data | ![]() PDB-3wru: |
Chemicals | ![]() ChemComp-SJP: ![]() ChemComp-K: ![]() ChemComp-HOH: |
![]() | RNA/antibiotic / ribosomal RNA / aminoglycoside / RNA-antibiotic complex |