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TitleNon-ATP-Mimetic Organometallic Protein Kinase Inhibitor
Journal, issue, pagesChemistryOpen, Vol. 2, Page 180-185, Year 2013
Publish dateJul 2, 2013 (structure data deposition date)
AuthorsWahler, K. / Kraling, K. / Steuber, H. / Meggers, E.
External linksChemistryOpen / PubMed:24551564
MethodsX-ray diffraction
Resolution1.954 Å
Structure data

PDB-3we8:
Pim-1 kinase in complex with Ruthenium-based inhibitor
Method: X-RAY DIFFRACTION / Resolution: 1.954 Å

Chemicals

ChemComp-RUI:
Cyclopentadienyl(carbon monoxide)(7-oxo-7,10-dihydro-1,8-phenanthrolin-10-yl-kappa~2~C~10~,N~1~)ruthenium

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE/TRANSFERASE INHIBITOR / kinase / TRANSFERASE-TRANSFERASE INHIBITOR complex

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