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Structure paper

TitleFlexibility and multiple conformations of the activation and glycine rich loops of aurora A accompanying inhibitor binding
Journal, issue, pagesTo be Published
Publish dateNov 28, 2012 (structure data deposition date)
AuthorsOliveira, T.M. / Kairies, N. / Engh, R.A.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.45 Å
Structure data

PDB-3w2c:
Structure of Aurora kinase A complexed to benzoimidazole-indazole inhibitor XV
Method: X-RAY DIFFRACTION / Resolution: 2.45 Å

Chemicals

ChemComp-N15:
2-{4-[3-(1H-benzimidazol-2-yl)-1H-indazol-6-yl]-1H-pyrazol-1-yl}-N-(3-methylbutyl)acetamide

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / kinase / ATP competitor

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