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-Structure paper
Title | Structure-based design, synthesis, and evaluation of imidazo[1,2-b]pyridazine and imidazo[1,2-a]pyridine derivatives as novel dual c-Met and VEGFR2 kinase inhibitors. |
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Journal, issue, pages | Bioorg. Med. Chem., Vol. 21, Page 7686-7698, Year 2013 |
Publish date | Aug 8, 2012 (structure data deposition date) |
![]() | Matsumoto, S. / Miyamoto, N. / Hirayama, T. / Oki, H. / Okada, K. / Tawada, M. / Iwata, H. / Nakamura, K. / Yamasaki, S. / Miki, H. ...Matsumoto, S. / Miyamoto, N. / Hirayama, T. / Oki, H. / Okada, K. / Tawada, M. / Iwata, H. / Nakamura, K. / Yamasaki, S. / Miki, H. / Hori, A. / Imamura, S. |
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Methods | X-ray diffraction |
Resolution | 2.1 Å |
Structure data | ![]() PDB-3vw8: |
Chemicals | ![]() ChemComp-DF6: ![]() ChemComp-CL: ![]() ChemComp-HOH: |
Source |
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![]() | TRANSFERASE/TRANSFERASE INHIBITOR / Transferase / TRANSFERASE-TRANSFERASE INHIBITOR complex |