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Structure paper

TitleCrystal structure of mitochondrial quinol-fumarate reductase from the parasitic nematode Ascaris suum
Journal, issue, pagesJ. Biochem., Vol. 151, Page 589-592, Year 2012
Publish dateApr 7, 2012 (structure data deposition date)
AuthorsShimizu, H. / Osanai, A. / Sakamoto, K. / Inaoka, D.K. / Shiba, T. / Harada, S. / Kita, K.
External linksJ. Biochem. / PubMed:22577165
MethodsX-ray diffraction
Resolution2.81 - 2.91 Å
Structure data

PDB-3vr8:
Mitochondrial rhodoquinol-fumarate reductase from the parasitic nematode Ascaris suum
Method: X-RAY DIFFRACTION / Resolution: 2.81 Å

PDB-3vrb:
Mitochondrial rhodoquinol-fumarate reductase from the parasitic nematode Ascaris suum with the specific inhibitor flutolanil and substrate fumarate
Method: X-RAY DIFFRACTION / Resolution: 2.91 Å

Chemicals

ChemComp-MLI:
MALONATE ION

ChemComp-FAD:
FLAVIN-ADENINE DINUCLEOTIDE / FAD*YM

ChemComp-FES:
FE2/S2 (INORGANIC) CLUSTER

ChemComp-SF4:
IRON/SULFUR CLUSTER

ChemComp-F3S:
FE3-S4 CLUSTER

ChemComp-HEM:
PROTOPORPHYRIN IX CONTAINING FE

ChemComp-RQX:
2-amino-3-methoxy-6-methyl-5-[(2E)-3-methylhex-2-en-1-yl]cyclohexa-2,5-diene-1,4-dione

ChemComp-EPH:
L-ALPHA-PHOSPHATIDYL-BETA-OLEOYL-GAMMA-PALMITOYL-PHOSPHATIDYLETHANOLAMINE / phospholipid*YM

ChemComp-FUM:
FUMARIC ACID

ChemComp-FTN:
N-[3-(1-methylethoxy)phenyl]-2-(trifluoromethyl)benzamide

Source
  • ascaris suum (pig roundworm)
KeywordsOXIDOREDUCTASE / Ascaris suum / membrane protein / reductase / mitochondria membrane / OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR / mitochondrial membrane / OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex

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