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-Structure paper
Title | Rational evolution of a novel type of potent and selective proviral integration site in Moloney murine leukemia virus kinase 1 (PIM1) inhibitor from a screening-hit compound. |
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Journal, issue, pages | J. Med. Chem., Vol. 55, Page 5151-5164, Year 2012 |
Publish date | Nov 14, 2011 (structure data deposition date) |
![]() | Nakano, H. / Saito, N. / Parker, L.J. / Tada, Y. / Abe, M. / Tsuganezawa, K. / Yokoyama, S. / Tanaka, A. / Kojima, H. / Okabe, T. / Nagano, T. |
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Methods | X-ray diffraction |
Resolution | 2.08 Å |
Structure data | ![]() PDB-3umw: |
Chemicals | ![]() ChemComp-GOL: ![]() ChemComp-SO4: ![]() ChemComp-596: ![]() ChemComp-HOH: |
Source |
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![]() | TRANSFERASE/INHIBITOR / PIM1 / kinase inhibitor / rational drug design / leukemia / TRANSFERASE-INHIBITOR complex |