+Search query
-Structure paper
Title | Structural and enzymatic analyses reveal the binding mode of a novel series of Francisella tularensis enoyl reductase (FabI) inhibitors. |
---|---|
Journal, issue, pages | J. Med. Chem., Vol. 55, Page 5933-5941, Year 2012 |
Publish date | Nov 4, 2011 (structure data deposition date) |
Authors | Mehboob, S. / Hevener, K.E. / Truong, K. / Boci, T. / Santarsiero, B.D. / Johnson, M.E. |
External links | J. Med. Chem. / PubMed:22642319 |
Methods | X-ray diffraction |
Resolution | 2.5 Å |
Structure data | PDB-3uic: |
Chemicals | ChemComp-NAD: ChemComp-09T: ChemComp-HOH: |
Source |
|
Keywords | OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR / Rossmann Fold / Enoyl Reductase / NADH Binding / OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex |