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TitleIn Vitro Validation of Acetyltransferase Activity of GlmU as an Antibacterial Target in Haemophilus influenzae.
Journal, issue, pagesJ. Biol. Chem., Vol. 286, Page 40734-40742, Year 2011
Publish dateSep 21, 2011 (structure data deposition date)
AuthorsBuurman, E.T. / Andrews, B. / Gao, N. / Hu, J. / Keating, T.A. / Lahiri, S. / Otterbein, L.R. / Patten, A.D. / Stokes, S.S. / Shapiro, A.B.
External linksJ. Biol. Chem. / PubMed:21984832
MethodsX-ray diffraction
Resolution1.9 Å
Structure data

PDB-3twd:
glmuC1 in complex with an antibacterial inhibitor
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-GOB:
4-({5-[(4-aminophenyl)(phenyl)sulfamoyl]-2,4-dimethoxyphenyl}amino)-4-oxobutanoic acid

ChemComp-HOH:
WATER

Source
  • escherichia coli (E. coli)
KeywordsTRANSFERASE/TRANSFERASE INHIBITOR / acetyl transferase / uridyl transferase / TRANSFERASE-TRANSFERASE INHIBITOR complex

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