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-Structure paper
Title | Pyrrolamide DNA gyrase inhibitors: Optimization of antibacterial activity and efficacy. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 21, Page 7416-7420, Year 2011 |
Publish date | Sep 15, 2011 (structure data deposition date) |
![]() | Sherer, B.A. / Hull, K. / Green, O. / Basarab, G. / Hauck, S. / Hill, P. / Loch, J.T. / Mullen, G. / Bist, S. / Bryant, J. ...Sherer, B.A. / Hull, K. / Green, O. / Basarab, G. / Hauck, S. / Hill, P. / Loch, J.T. / Mullen, G. / Bist, S. / Bryant, J. / Boriack-Sjodin, A. / Read, J. / Degrace, N. / Uria-Nickelsen, M. / Illingworth, R.N. / Eakin, A.E. |
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Methods | X-ray diffraction |
Resolution | 1.63 Å |
Structure data | ![]() PDB-3ttz: |
Chemicals | ![]() ChemComp-07N: ![]() ChemComp-MG: ![]() ChemComp-HOH: |
Source |
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![]() | ISOMERASE/ISOMERASE INHIBITOR / protein-inhibitor complex / ATP-binding / structure-based drug design / antimicrobial / ISOMERASE-ISOMERASE INHIBITOR complex |