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-Structure paper
Title | Dual dehydrosqualene/squalene synthase inhibitors: leads for innate immune system-based therapeutics. |
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Journal, issue, pages | Chemmedchem, Vol. 7, Page 561-564, Year 2012 |
Publish date | Aug 16, 2011 (structure data deposition date) |
Authors | Lin, F.Y. / Zhang, Y. / Hensler, M. / Liu, Y.L. / Chow, O.A. / Zhu, W. / Wang, K. / Pang, R. / Thienphrapa, W. / Nizet, V. / Oldfield, E. |
External links | Chemmedchem / PubMed:22290830 |
Methods | X-ray diffraction |
Resolution | 2 - 3 Å |
Structure data | PDB-3tfn: PDB-3tfp: PDB-3tfv: |
Chemicals | ChemComp-2CJ: ChemComp-MG: ChemComp-HOH: ChemComp-03L: ChemComp-2CN: |
Source |
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Keywords | TRANSFERASE/transferase inhibitor / head to head prenyl synthase / TRANSFERASE-transferase inhibitor complex / Head-to-Head Prenyl Synthase |