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Structure paper

TitleThe bacterial redox signaller pyocyanin as an antiplasmodial agent: comparisons with its thioanalog methylene blue.
Journal, issue, pagesRedox Rep., Vol. 16, Page 154-165, Year 2011
Publish dateJul 6, 2011 (structure data deposition date)
AuthorsKasozi, D.M. / Gromer, S. / Adler, H. / Zocher, K. / Rahlfs, S. / Wittlin, S. / Fritz-Wolf, K. / Schirmer, R.H. / Becker, K.
External linksRedox Rep. / PubMed:21888766
MethodsX-ray diffraction
Resolution2.21 Å
Structure data

PDB-3sqp:
Structure of human glutathione reductase complexed with pyocyanin, an agent with antimalarial activity
Method: X-RAY DIFFRACTION / Resolution: 2.21 Å

Chemicals

ChemComp-FAD:
FLAVIN-ADENINE DINUCLEOTIDE / FAD*YM

ChemComp-SO4:
SULFATE ION

ChemComp-3J8:
5-methylphenazin-1(5H)-one

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsOXIDOREDUCTASE/ANTIBIOTIC / CELLULAR REDUCTANTS / GLUTATHIONE REDUCTASE / PLASMODIUM FALCIPARUM / PYOCYANIN / ALTERNATIVE INITIATION / FLAVOPROTEIN / MITOCHONDRION / OXIDOREDUCTASE / PHOSPHOPROTEIN / REDOX-ACTIVE CENTER / TRANSIT PEPTIDE / OXIDOREDUCTASE-ANTIBIOTIC complex

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