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Structure paper

TitleA CAL Inhibitor with Single-PDZ Specificity Rescues deltaF508-CFTR
Journal, issue, pagesTo be Published
Publish dateJun 13, 2011 (structure data deposition date)
AuthorsCushing, P.R. / Amacher, J.F. / Vouilleme, L. / Culatti, S. / Deng, B. / Gerber, S.A. / Boisguerin, P. / Madden, D.R.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.24 - 1.6 Å
Structure data

PDB-3sfj:
Crystal Structure of Tax-Interacting Protein-1 (TIP-1) PDZ domain bound to iCAL36 inhibitor peptide
Method: X-RAY DIFFRACTION / Resolution: 1.24 Å

PDB-4nnl:
Tax-Interacting Protein-1 (TIP-1) PDZ domain bound to F-iCAL36 (ANSRFPTSII) peptide
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

PDB-4nnm:
Tax-Interacting Protein-1 (TIP-1) PDZ domain bound to Y-iCAL36 (YPTSII) peptide
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-GOL:
GLYCEROL

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN/INHIBITOR / PDZ:peptide complex / SIGNALING PROTEIN-INHIBITOR complex / PROTEIN BINDING / Tax-Interacting Protein-1 / TIP-1 / PDZ / PDZ-peptide

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