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-Structure paper
Title | Structural analysis of human dihydrofolate reductase as a binary complex with the potent and selective inhibitor 2,4-diamino-6-{2'-O-(3-carboxypropyl)oxydibenz[b,f]-azepin-5-yl}methylpteridine reveals an unusual binding mode. |
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Journal, issue, pages | Acta Crystallogr. ,Sect. D, Vol. 67, Page 875-880, Year 2011 |
Publish date | May 26, 2011 (structure data deposition date) |
![]() | Cody, V. / Pace, J. / Nowak, J. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 1.8 Å |
Structure data | ![]() PDB-3s7a: |
Chemicals | ![]() ChemComp-SO4: ![]() ChemComp-684: ![]() ChemComp-HOH: |
Source |
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![]() | OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR / single polypeptide chain / reductase / OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex |