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-Structure paper
Title | Structures of cytochrome P450 17A1 with prostate cancer drugs abiraterone and TOK-001. |
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Journal, issue, pages | Nature, Vol. 482, Page 116-119, Year 2012 |
Publish date | May 5, 2011 (structure data deposition date) |
![]() | Devore, N.M. / Scott, E.E. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.4 - 2.6 Å |
Structure data | ![]() PDB-3ruk: ![]() PDB-3swz: |
Chemicals | ![]() ChemComp-HEM: ![]() ChemComp-AER: ![]() ChemComp-HOH: ![]() ChemComp-TOK: |
Source |
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![]() | OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR / cytochrome P450 / CYP17A1 / P450 17A1 / monooxygenase / 17a-hydroxylase / 17 / 20-lyase / heme protein / cytochrome P450 oxidoreductase / Abiraterone / Zytiga / 17a-hydroxylation / membrane / microsome / endoplasmic reticulum / Galeterone / OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex / P450 / P450c17 / TOK-001 / VN/124-1 |