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Structure paper

TitleStructural and functional characterization of a novel nonglycosidic type I NKT agonist with immunomodulatory properties.
Journal, issue, pagesJ. Immunol., Vol. 188, Page 2254-2265, Year 2012
Publish dateMay 3, 2011 (structure data deposition date)
AuthorsKerzerho, J. / Yu, E.D. / Barra, C.M. / Alari-Pahisa, E. / Girardi, E. / Harrak, Y. / Lauzurica, P. / Llebaria, A. / Zajonc, D.M. / Akbari, O. / Castano, A.R.
External linksJ. Immunol. / PubMed:22301545
MethodsX-ray diffraction
Resolution2.8 Å
Structure data

PDB-3rtq:
Structure of the mouse CD1d-HS44-iNKT TCR complex
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-H4S:
N-[(2S,3S,4R)-3,4-dihydroxy-1-{[(1S,2S,3R,4R,5S)-2,3,4,5-tetrahydroxycyclohexyl]amino}octadecan-2-yl]hexacosanamide

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / antigen presentation / glycolipid / NKT cells

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