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Structure paper

TitleConserved catalytic residues of the ALDH1L1 aldehyde dehydrogenase domain control binding and discharging of the coenzyme.
Journal, issue, pagesJ. Biol. Chem., Vol. 286, Page 23357-23367, Year 2011
Publish dateApr 11, 2011 (structure data deposition date)
AuthorsTsybovsky, Y. / Krupenko, S.A.
External linksJ. Biol. Chem. / PubMed:21540484
MethodsX-ray diffraction
Resolution1.89 - 2.5 Å
Structure data

PDB-3rhj:
Crystal structure of the E673A mutant of the C-terminal domain of RAT 10'FORMYLTETRAHYDROFOLATE DEHYDROGENASE in complex with co-purified NADP
Method: X-RAY DIFFRACTION / Resolution: 1.89 Å

PDB-3rhl:
Crystal structure of the E673A/C707A double mutant of the C-Terminal domain of RAT 10'FORMYLTETRAHYDROFOLATE DEHYDROGENASE in complex with co-purified NADP
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-3rhm:
Crystal structure of the E673Q mutant oF C-Terminal domain of 10'FORMYLTETRAHYDROFOLATE DEHYDROGENASE
Method: X-RAY DIFFRACTION / Resolution: 2.38 Å

PDB-3rho:
Crystal structure of the E673Q MUTANT OF C-Terminal domain of 10'FORMYLTETRAHYDROFOLATE DEHYDROGENASE in complex with NADP
Method: X-RAY DIFFRACTION / Resolution: 2.26 Å

PDB-3rhp:
Crystal structure of the C707A mutant of the C-Terminal domain of 10'FORMYLTETRAHYDROFOLATE DEHYDROGENASE
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-3rhq:
Crystal structure of the C707A mutant of C-Terminal domain of 10'FORMYLTETRAHYDROFOLATE DEHYDROGENASE in complex with NADP
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-3rhr:
Crystal structure of the C707A mutant of the C-Terminal domain of 10'FORMYLTETRAHYDROFOLATE DEHYDROGENASE in complex with NADPH
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-NAP:
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

ChemComp-SO4:
SULFATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-NDP:
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

Source
  • rattus norvegicus (Norway rat)
KeywordsOXIDOREDUCTASE / FDH

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