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-Structure paper
Title | Discovery and structural characterization of a small molecule 14-3-3 protein-protein interaction inhibitor. |
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Journal, issue, pages | Proc. Natl. Acad. Sci. USA, Vol. 108, Page 16212-16216, Year 2011 |
Publish date | Apr 1, 2011 (structure data deposition date) |
Authors | Zhao, J. / Du, Y. / Horton, J.R. / Upadhyay, A.K. / Lou, B. / Bai, Y. / Zhang, X. / Du, L. / Li, M. / Wang, B. ...Zhao, J. / Du, Y. / Horton, J.R. / Upadhyay, A.K. / Lou, B. / Bai, Y. / Zhang, X. / Du, L. / Li, M. / Wang, B. / Zhang, L. / Barbieri, J.T. / Khuri, F.R. / Cheng, X. / Fu, H. |
External links | Proc. Natl. Acad. Sci. USA / PubMed:21908710 |
Methods | X-ray diffraction |
Resolution | 2.39 Å |
Structure data | PDB-3rdh: |
Chemicals | ChemComp-3RD: ChemComp-NI: ChemComp-HOH: |
Source |
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Keywords | SIGNALING PROTEIN/INHIBITOR / phosphoSer/Thr-mimetic agent / phosphoserine/threonine-recognition protein / SIGNALING PROTEIN-INHIBITOR complex |