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Structure paper

TitleStructural basis for retinoic x receptor repression on the tetramer.
Journal, issue, pagesJ. Biol. Chem., Vol. 286, Page 24593-24598, Year 2011
Publish dateMar 14, 2011 (structure data deposition date)
AuthorsZhang, H. / Chen, L. / Chen, J. / Jiang, H. / Shen, X.
External linksJ. Biol. Chem. / PubMed:21613212
MethodsX-ray diffraction
Resolution2.9 - 3 Å
Structure data

PDB-3r29:
Crystal structure of RXRalpha ligand-binding domain complexed with corepressor SMRT2
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

PDB-3r2a:
Crystal structure of RXRalpha ligand-binding domain complexed with corepressor SMRT2 and antagonist rhein
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-RHN:
4,5-dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / nuclear receptor / transcription factor / ligand-binding domain

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