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-Structure paper
Title | Structures of Cytochrome P450 2B6 Bound to 4-Benzylpyridine and 4-(4-Nitrobenzyl)pyridine: Insight into Inhibitor Binding and Rearrangement of Active Site Side Chains. |
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Journal, issue, pages | Mol. Pharmacol., Vol. 80, Page 1047-1055, Year 2011 |
Publish date | Feb 9, 2011 (structure data deposition date) |
Authors | Shah, M.B. / Pascual, J. / Zhang, Q. / Stout, C.D. / Halpert, J.R. |
External links | Mol. Pharmacol. / PubMed:21875942 |
Methods | X-ray diffraction |
Resolution | 2.1 - 2.8 Å |
Structure data | PDB-3qoa: PDB-3qu8: |
Chemicals | ChemComp-HEM: ChemComp-CM5: ChemComp-3QO: ChemComp-HOH: ChemComp-3QU: |
Source |
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Keywords | OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR / P450 / CYTOCHROME P450 2B6 / MONOOXYGENASE / MEMBRANE PROTEIN / CYP2B6 / ENDOPLASMIC RETICULUM / HEME / IRON / MEMBRANE / METAL BINDING / MIRCOSOME / PHOSPHOPROTEIN / OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex / MICROSOME |