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Structure paper

TitleCrystal structure of dipeptidyl peptidase IV in complex with inhibitor
Journal, issue, pagesTo be Published
Publish dateJan 13, 2011 (structure data deposition date)
AuthorsLiu, S.P.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.21 Å
Structure data

PDB-3qbj:
Crystal structure of dipeptidyl peptidase IV in complex with inhibitor
Method: X-RAY DIFFRACTION / Resolution: 2.21 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-NXZ:
1-[(3S,4S)-4-amino-1-(6-phenylpyrimidin-4-yl)pyrrolidin-3-yl]piperidin-2-one

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
Keywordshydrolase/hydrolase inhibitor / Diabetes Mellitus / Dipeptidyl-Peptidase IV Inhibitor / Hypoglycemic Agent / Pyrrolidines / Sprague-Dawley / Structure-Activity Relationship / hydrolase / glycosylation / hydrolase-hydrolase inhibitor complex

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