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Title6-amino-4-(pyrimidin-4-yl)pyridones: novel glycogen synthase kinase-3β inhibitors
Journal, issue, pagesBioorg. Med. Chem. Lett., Vol. 21, Page 1429-1433, Year 2011
Publish dateDec 21, 2010 (structure data deposition date)
AuthorsCoffman, K. / Brodney, M. / Cook, J. / Lanyon, L. / Pandit, J. / Sakya, S. / Schachter, J. / Tseng-Lovering, E. / Wessel, M.
External linksBioorg. Med. Chem. Lett. / PubMed:21295469
MethodsX-ray diffraction
Resolution2.7 Å
Structure data

PDB-3q3b:
6-Amino-4-(pyrimidin-4-yl)pyridones: Novel Glycogen Synthase Kinase-3 Inhibitors
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Chemicals

ChemComp-55E:
4-(4-hydroxy-3-methylphenyl)-6-phenylpyrimidin-2(5H)-one

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE/TRANSFERASE INHIBITOR / Kinase / Inhibitor / TRANSFERASE-TRANSFERASE INHIBITOR complex

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