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TitleStructural features underlying the selectivity of the kinase inhibitors NBC and dNBC: role of a nitro group that discriminates between CK2 and DYRK1A
Journal, issue, pagesCell. Mol. Life Sci., Vol. 69, Page 449-460, Year 2012
Publish dateDec 8, 2010 (structure data deposition date)
AuthorsSarno, S. / Mazzorana, M. / Traynor, R. / Ruzzene, M. / Cozza, G. / Pagano, M.A. / Meggio, F. / Zagotto, G. / Battistutta, R. / Pinna, L.A.
External linksCell. Mol. Life Sci. / PubMed:21720886
MethodsX-ray diffraction
Resolution2.2 Å
Structure data

PDB-3pwd:
Crystal structure of maize CK2 in complex with NBC (Z1)
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-CZ0:
8-hydroxy-4-methyl-9-nitro-2H-benzo[g]chromen-2-one

ChemComp-HOH:
WATER

Source
  • zea mays (maize)
KeywordsTRANSFERASE/TRANSFERASE INHIBITOR / protein kinase / inhibitor / TRANSFERASE-TRANSFERASE INHIBITOR complex

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