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Structure paper

TitleStructure of DNMT1-DNA complex reveals a role for autoinhibition in maintenance DNA methylation.
Journal, issue, pagesScience, Vol. 331, Page 1036-1040, Year 2011
Publish dateDec 2, 2010 (structure data deposition date)
AuthorsSong, J. / Rechkoblit, O. / Bestor, T.H. / Patel, D.J.
External linksScience / PubMed:21163962
MethodsX-ray diffraction
Resolution2.5 - 3.6 Å
Structure data

PDB-3pt6:
Crystal structure of mouse DNMT1(650-1602) in complex with DNA
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-3pt9:
Crystal structure of mouse DNMT1(731-1602) in the free state
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-3pta:
Crystal structure of human DNMT1(646-1600) in complex with DNA
Method: X-RAY DIFFRACTION / Resolution: 3.6 Å

Chemicals

ChemComp-SAH:
S-ADENOSYL-L-HOMOCYSTEINE

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • homo sapiens (human)
KeywordsTransferase/DNA / Maintenance DNA methylation / Transferase-DNA complex / TRANSFERASE / DNMT1

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