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Structure paper

TitleSelective inactivation of a human neuronal silencing phosphatase by a small molecule inhibitor.
Journal, issue, pagesAcs Chem. Biol., Vol. 6, Page 511-519, Year 2011
Publish dateNov 2, 2010 (structure data deposition date)
AuthorsZhang, M. / Cho, E.J. / Burstein, G. / Siegel, D. / Zhang, Y.
External linksAcs Chem. Biol. / PubMed:21348431
MethodsX-ray diffraction
Resolution2.35 Å
Structure data

PDB-3pgl:
Crystal structure of human small C-terminal domain phosphatase 1 (Scp1) bound to rabeprazole
Method: X-RAY DIFFRACTION / Resolution: 2.35 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-RZX:
2-[(R)-{[4-(3-methoxypropoxy)-3-methylpyridin-2-yl]methyl}sulfinyl]-1H-benzimidazole / medication*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE/HYDROLASE INHIBITOR / HAD family / insertion domain / CTD phosphatase / neuronal silencer / HYDROLASE-HYDROLASE INHIBITOR complex

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