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TitleCrystal structures of active and inhibitor-bound human Casp6
Journal, issue, pagesTo be Published
Publish dateOct 6, 2010 (structure data deposition date)
AuthorsMueller, I. / Lamers, M.B.A.C. / Ritchie, A.J. / Dominquez, C. / Munoz, I. / Maillard, M. / Kiselyov, A.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.9 - 2.53 Å
Structure data

PDB-3p45:
Crystal structure of apo-caspase-6 at physiological pH
Method: X-RAY DIFFRACTION / Resolution: 2.53 Å

PDB-3p4u:
Crystal structure of active caspase-6 in complex with Ac-VEID-CHO inhibitor
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / protease / Huntington's disease / mature apo-caspase-6 / physiological pH / competitive inhibition / HYDROLASE/HYDROLASE INHIBITOR / caspase / HYDROLASE-HYDROLASE INHIBITOR complex

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