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-Structure paper
Title | Selective irreversible inhibition of a protease by targeting a noncatalytic cysteine. |
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Journal, issue, pages | Nat. Chem. Biol., Vol. 7, Page 22-24, Year 2011 |
Publish date | Sep 23, 2010 (structure data deposition date) |
![]() | Hagel, M. / Niu, D. / St.Martin, T. / Sheets, M.P. / Qiao, L. / Bernard, H. / Karp, R.M. / Zhu, Z. / Labenski, M.T. / Chaturvedi, P. ...Hagel, M. / Niu, D. / St.Martin, T. / Sheets, M.P. / Qiao, L. / Bernard, H. / Karp, R.M. / Zhu, Z. / Labenski, M.T. / Chaturvedi, P. / Nacht, M. / Westlin, W.F. / Petter, R.C. / Singh, J. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.76 Å |
Structure data | ![]() PDB-3oyp: |
Chemicals | ![]() ChemComp-ZN: ![]() ChemComp-HOH: |
Source |
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![]() | HYDROLASE/HYDROLASE INHIBITOR / SERINE PROTEASE / NS3 / NS4A / HEPATITIS C VIRUS / PROTEASE INHIBITION / HYDROLASE-HYDROLASE INHIBITOR complex |