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-Structure paper
Title | Substituted pyrazoles as novel sEH antagonist: investigation of key binding interactions within the catalytic domain. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 20, Page 6379-6383, Year 2010 |
Publish date | Sep 13, 2010 (structure data deposition date) |
Authors | Lo, H.Y. / Man, C.C. / Fleck, R.W. / Farrow, N.A. / Ingraham, R.H. / Kukulka, A. / Proudfoot, J.R. / Betageri, R. / Kirrane, T. / Patel, U. ...Lo, H.Y. / Man, C.C. / Fleck, R.W. / Farrow, N.A. / Ingraham, R.H. / Kukulka, A. / Proudfoot, J.R. / Betageri, R. / Kirrane, T. / Patel, U. / Sharma, R. / Hoermann, M.A. / Kabcenell, A. / Lombaert, S.D. |
External links | Bioorg. Med. Chem. Lett. / PubMed:20934334 |
Methods | X-ray diffraction |
Resolution | 3 Å |
Structure data | PDB-3otq: |
Chemicals | ChemComp-MZL: ChemComp-HOH: |
Source |
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Keywords | HYDROLASE / epoxide hydrolase |