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-Structure paper
Title | Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists. |
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Journal, issue, pages | Science, Vol. 330, Page 1066-1071, Year 2010 |
Publish date | Aug 11, 2010 (structure data deposition date) |
![]() | Wu, B. / Chien, E.Y. / Mol, C.D. / Fenalti, G. / Liu, W. / Katritch, V. / Abagyan, R. / Brooun, A. / Wells, P. / Bi, F.C. ...Wu, B. / Chien, E.Y. / Mol, C.D. / Fenalti, G. / Liu, W. / Katritch, V. / Abagyan, R. / Brooun, A. / Wells, P. / Bi, F.C. / Hamel, D.J. / Kuhn, P. / Handel, T.M. / Cherezov, V. / Stevens, R.C. |
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Methods | X-ray diffraction |
Resolution | 2.5 - 3.2 Å |
Structure data | ![]() PDB-3odu: ![]() PDB-3oe0: ![]() PDB-3oe6: ![]() PDB-3oe8: ![]() PDB-3oe9: |
Chemicals | ![]() ChemComp-ITD: ![]() ChemComp-OLC: ![]() ChemComp-OLA: ![]() ChemComp-HOH: ![]() ChemComp-GOL: |
Source |
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![]() | SIGNALING PROTEIN / HYDROLASE / Structural Genomics / PSI-2 / Protein Structure Initiative / Accelerated Technologies Center for Gene to 3D Structure / ATCG3D / 7TM / G protein-coupled receptor / GPCR / Signal transduction / Cancer / HIV-1 co-receptor / chemokine / CXCL12 / SDF1 / isothiourea / Chimera / T4L Fusion / Membrane protein / Transmembrane / SINGNALING PROTEIN / PSI-Biology / GPCR Network / HYDROLASE/ANTIBIOTIC / antimicrobial / antibiotic / polyphemusin / HYDROLASE-ANTIBIOTIC complex / IT1t / chemotaxis |