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-Structure paper
Title | A novel series of positive modulators of the AMPA receptor: structure-based lead optimization. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 20, Page 6072-6075, Year 2010 |
Publish date | Jul 29, 2010 (structure data deposition date) |
Authors | Jamieson, C. / Campbell, R.A. / Cumming, I.A. / Gillen, K.J. / Gillespie, J. / Kazemier, B. / Kiczun, M. / Lamont, Y. / Lyons, A.J. / Maclean, J.K. ...Jamieson, C. / Campbell, R.A. / Cumming, I.A. / Gillen, K.J. / Gillespie, J. / Kazemier, B. / Kiczun, M. / Lamont, Y. / Lyons, A.J. / Maclean, J.K. / Martin, F. / Moir, E.M. / Morrow, J.A. / Pantling, J. / Rankovic, Z. / Smith, L. |
External links | Bioorg. Med. Chem. Lett. / PubMed:20817521 |
Methods | X-ray diffraction |
Resolution | 1.8 - 2.1 Å |
Structure data | PDB-3o6g: PDB-3o6h: PDB-3o6i: |
Chemicals | ChemComp-GLU: ChemComp-SO4: ChemComp-O27: ChemComp-EDO: ChemComp-HOH: ChemComp-O25: ChemComp-DMS: ChemComp-O26: |
Source |
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Keywords | TRANSPORT PROTEIN / Membrane Protein / Fusion protein / chimera protein |