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-Structure paper
Title | 20S proteasome inhibition: designing noncovalent linear peptide mimics of the natural product TMC-95A. |
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Journal, issue, pages | Chemmedchem, Vol. 5, Page 1701-1705, Year 2010 |
Publish date | Jul 16, 2010 (structure data deposition date) |
Authors | Groll, M. / Gallastegui, N. / Marechal, X. / Le Ravalec, V. / Basse, N. / Richy, N. / Genin, E. / Huber, R. / Moroder, L. / Vidal, J. / Reboud-Ravaux, M. |
External links | Chemmedchem / PubMed:20715286 |
Methods | X-ray diffraction |
Resolution | 2.4 - 2.7 Å |
Structure data | PDB-3nzj: PDB-3nzw: PDB-3nzx: |
Chemicals | ChemComp-MES: ChemComp-HOH: |
Source |
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Keywords | hydrolase/hydrolase inhibitor / ubiquitin / protein degradation / N-terminal nucleophilic hydrolase / 19S regulatory particle / ubiquitin-tagged substrates / cytosol / nucleus / hydrolase-hydrolase inhibitor complex |