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Structure paper

TitleSubstrate-induced remodeling of the active site regulates human HTRA1 activity.
Journal, issue, pagesNat. Struct. Mol. Biol., Vol. 18, Page 386-388, Year 2011
Publish dateJul 7, 2010 (structure data deposition date)
AuthorsTruebestein, L. / Tennstaedt, A. / Monig, T. / Krojer, T. / Canellas, F. / Kaiser, M. / Clausen, T. / Ehrmann, M.
External linksNat. Struct. Mol. Biol. / PubMed:21297635
MethodsX-ray diffraction
Resolution2.75 - 3.2 Å
Structure data

PDB-3num:
Substrate induced remodeling of the active site regulates HtrA1 activity
Method: X-RAY DIFFRACTION / Resolution: 2.75 Å

PDB-3nwu:
Substrate induced remodeling of the active site regulates HtrA1 activity
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

PDB-3nzi:
Substrate induced remodeling of the active site regulates HtrA1 activity
Method: X-RAY DIFFRACTION / Resolution: 2.75 Å

Chemicals

ChemComp-SO4:
SULFATE ION

Source
  • homo sapiens (human)
KeywordsHYDROLASE / serine protease / DegP / HtrA / protease / hydrolase/hydrolase substrate / hydrolase-peptide inhibitor complex / hydrolase-hydrolase substrate complex

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