+Search query
-Structure paper
Title | Probing the inhibitor selectivity pocket of human 20 alpha-hydroxysteroid dehydrogenase (AKR1C1) with X-ray crystallography and site-directed mutagenesis |
---|---|
Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 21, Page 2564-2567, Year 2011 |
Publish date | Jul 6, 2010 (structure data deposition date) |
Authors | El-Kabbani, O. / Dhagat, U. / Soda, M. / Endo, S. / Matsunaga, T. / Hara, A. |
External links | Bioorg. Med. Chem. Lett. / PubMed:21414777 |
Methods | X-ray diffraction |
Resolution | 1.87 Å |
Structure data | PDB-3nty: |
Chemicals | ChemComp-NAP: ChemComp-5P3: ChemComp-ZN: ChemComp-HOH: |
Source |
|
Keywords | OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR / Aldo-keto reductase / 20 alpha hydroxysteroid dehydrogenase / AKR1C1 / OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex |