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-Structure paper
Title | Switch control pocket inhibitors of p38-MAP kinase. Durable type II inhibitors that do not require binding into the canonical ATP hinge region |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 20, Page 5793-5798, Year 2010 |
Publish date | Jun 24, 2010 (structure data deposition date) |
![]() | Ahn, Y.M. / Clare, M. / Ensinger, C.L. / Hood, M.M. / Lord, J.W. / Lu, W.P. / Miller, D.F. / Patt, W.C. / Smith, B.D. / Vogeti, L. ...Ahn, Y.M. / Clare, M. / Ensinger, C.L. / Hood, M.M. / Lord, J.W. / Lu, W.P. / Miller, D.F. / Patt, W.C. / Smith, B.D. / Vogeti, L. / Kaufman, M.D. / Petillo, P.A. / Wise, S.C. / Abendroth, J. / Chun, L. / Clark, R. / Feese, M. / Kim, H. / Stewart, L. / Flynn, D.L. |
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Methods | X-ray diffraction |
Resolution | 1.89 - 2.4 Å |
Structure data | ![]() PDB-3nnu: ![]() PDB-3nnv: ![]() PDB-3nnw: ![]() PDB-3nnx: |
Chemicals | ![]() ChemComp-EDB: ![]() ChemComp-HOH: ![]() ChemComp-437: ![]() ChemComp-EDD: |
Source |
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![]() | TRANSFERASE / kinase |