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TitleContext-dependent cell cycle checkpoint abrogation by a novel kinase inhibitor
Journal, issue, pagesPlos One, Vol. 5, Page e13123-e13123, Year 2010
Publish dateJun 21, 2010 (structure data deposition date)
AuthorsMassey, A.J. / Borgognoni, J. / Bentley, C. / Foloppe, N. / Fiumana, A. / Walmsley, L.
External linksPlos One / PubMed:20976184
MethodsX-ray diffraction
Resolution1.9 Å
Structure data

PDB-3nlb:
Novel kinase profile highlights the temporal basis of context dependent checkpoint pathways to cell death
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-5BE:
3-methyl-5-[5-(1-methylethyl)-1H-benzimidazol-2-yl]-N-(1-methylpiperidin-4-yl)-1H-pyrazole-4-carboxamide

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE/TRANSFERASE INHIBITOR / Kinase Domain / Checkpoint Kinase / ATP Binding / Transferase / TRANSFERASE-TRANSFERASE INHIBITOR complex

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