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Structure paper

TitleClosed headpiece of integrin {alpha}IIb{beta}3 and its complex with an {alpha}IIb{beta}3-specific antagonist that does not induce opening.
Journal, issue, pagesBlood, Vol. 116, Page 5050-5059, Year 2010
Publish dateJun 15, 2010 (structure data deposition date)
AuthorsZhu, J.H. / Zhu, J.Q. / Negri, A. / Provasi, D. / Filizola, M. / Coller, B.S. / Springer, T.A.
External linksBlood / PubMed:20679525
MethodsX-ray diffraction
Resolution2.25 - 2.4 Å
Structure data

PDB-3nid:
The Closed Headpiece of Integrin alphaIIB beta3 and its Complex with an alpahIIB beta3 -Specific Antagonist That Does Not Induce Opening
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-3nif:
The Closed Headpiece of Integrin IIb 3 and its Complex with an IIb 3 -Specific Antagonist That Does Not Induce Opening
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-3nig:
The Closed Headpiece of Integrin IIb 3 and its Complex with an IIb 3 -Specific Antagonist That Does Not Induce Opening
Method: X-RAY DIFFRACTION / Resolution: 2.25 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-SO4:
SULFATE ION

ChemComp-MG:
Unknown entry

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-HOH:
WATER

ChemComp-NIF:
2-ethyl-7-piperazin-1-yl-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one

Source
  • homo sapiens (human)
  • mus musculus (house mouse)
KeywordsCELL ADHESION/BLOOD CLOTTING / Integrin / headpiece / alphaIIB / beta3 / CELL ADHESION-BLOOD CLOTTING complex / CELL ADHESION-IMMUNE SYSTEM complex

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