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Structure paper

TitleThe function and three-dimensional structure of a thromboxane a(2)/cysteinyl leukotriene-binding protein from the saliva of a mosquito vector of the malaria parasite.
Journal, issue, pagesPlos Biol., Vol. 8, Page e1000547-e1000547, Year 2010
Publish dateJun 13, 2010 (structure data deposition date)
AuthorsAlvarenga, P.H. / Francischetti, I.M. / Calvo, E. / Sa-Nunes, A. / Ribeiro, J.M. / Andersen, J.F.
External linksPlos Biol. / PubMed:21152418
MethodsX-ray diffraction
Resolution1.43 - 1.76 Å
Structure data

PDB-3ngv:
Crystal structure of AnSt-D7L1
Method: X-RAY DIFFRACTION / Resolution: 1.76 Å

PDB-3nhi:
Crystal structure of the AnSt-D7L1-leukotriene C4 complex
Method: X-RAY DIFFRACTION / Resolution: 1.43 Å

PDB-3nht:
Crystal structure of the AnSt-D7L1-U46619 complex
Method: X-RAY DIFFRACTION / Resolution: 1.45 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

ChemComp-EAH:
(5S,7E,9E,11Z,14Z)-5-hydroxyicosa-7,9,11,14-tetraenoic acid

ChemComp-U46:
(5E)-7-{6-[(1E)-3-HYDROXYOCT-1-ENYL]-2-OXABICYCLO[2.2.1]HEPT-5-YL}HEPT-5-ENOIC ACID

Source
  • anopheles stephensi (Asian malaria mosquito)
KeywordsTRANSPORT PROTEIN / All-helical / odorant-binding protein / D7 / Ligand binding protein / All helical / ligand-binding protein

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