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Structure paper

TitleStructural Basis for Proficient Incorporation of dTTP Opposite O6-Methylguanine by Human DNA Polymerase {iota}.
Journal, issue, pagesJ. Biol. Chem., Vol. 285, Page 40666-40672, Year 2010
Publish dateJun 11, 2010 (structure data deposition date)
AuthorsPence, M.G. / Choi, J.Y. / Egli, M. / Guengerich, F.P.
External linksJ. Biol. Chem. / PubMed:20961860
MethodsX-ray diffraction
Resolution1.9 - 2.8 Å
Structure data

PDB-3ngd:
Structural Basis for Proficient Incorporation of dTTP Opposite O6-methylguanine by Human DNA Polymerase Iota
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-3osn:
Structural Basis for Proficient Incorporation of dTTP Opposite O6-Methylguanine by Human DNA Polymerase Iota
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-DCP:
2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE

ChemComp-HOH:
WATER

ChemComp-TTP:
THYMIDINE-5'-TRIPHOSPHATE

ChemComp-MG:
Unknown entry

ChemComp-NA:
Unknown entry

Source
  • homo sapiens (human)
KeywordsTRANSFERASE/DNA / Hoogsteen Base Pair / Nucleoside Triphosphate / Y-family DNA polymerase / Translesion Synthesis / TRANSFERASE-DNA complex / Protein-DNA complex / O6-Methylguanine

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