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-Structure paper
Title | Structure-Based Design, Synthesis, and Structure-Activity Relationship Studies of HIV-1 Protease Inhibitors Incorporating Phenyloxazolidinones. |
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Journal, issue, pages | J. Med. Chem., Vol. 53, Page 7699-7708, Year 2010 |
Publish date | May 7, 2010 (structure data deposition date) |
Authors | Ali, A. / Reddy, G.S. / Nalam, M.N. / Anjum, S.G. / Cao, H. / Schiffer, C.A. / Rana, T.M. |
External links | J. Med. Chem. / PubMed:20958050 |
Methods | X-ray diffraction |
Resolution | 1.85 - 1.95 Å |
Structure data | PDB-3mxd: PDB-3mxe: |
Chemicals | ChemComp-K53: ChemComp-PO4: ChemComp-ACT: ChemComp-HOH: ChemComp-K54: |
Source |
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Keywords | HYDROLASE/HYDROLASE INHIBITOR / drug design / HIV-1 protease / protease inhibitors / HYDROLASE-HYDROLASE INHIBITOR complex / HIV protease / HYDROLASE |