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TitleAcyldepsipeptide antibiotics induce the formation of a structured axial channel in ClpP: A model for the ClpX/ClpA-bound state of ClpP.
Journal, issue, pagesChem. Biol., Vol. 17, Page 959-969, Year 2010
Publish dateApr 30, 2010 (structure data deposition date)
AuthorsLi, D.H. / Chung, Y.S. / Gloyd, M. / Joseph, E. / Ghirlando, R. / Wright, G.D. / Cheng, Y.Q. / Maurizi, M.R. / Guarne, A. / Ortega, J.
External linksChem. Biol. / PubMed:20851345
MethodsX-ray diffraction
Resolution1.901 Å
Structure data

PDB-3mt6:
Structure of ClpP from Escherichia coli in complex with ADEP1
Method: X-RAY DIFFRACTION / Resolution: 1.901 Å

Chemicals

ChemComp-MPD:
(4S)-2-METHYL-2,4-PENTANEDIOL / precipitant*YM

ChemComp-HOH:
WATER

Source
  • escherichia coli (E. coli)
  • streptomyces hawaiiensis (bacteria)
KeywordsHYDROLASE/ANTIBIOTIC / ENDOPEPTIDASE CLP / CASEINOLYTIC PROTEASE / PROTEASE TI / ACYPDEPSIPEPTIDE ANTIBIOTICS / HYDROLASE-ANTIBIOTIC COMPLEX

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