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TitleA ruthenium antimetastasis agent forms specific histone protein adducts in the nucleosome core
Journal, issue, pagesChemistry, Vol. 17, Page 3562-3566, Year 2011
Publish dateApr 22, 2010 (structure data deposition date)
AuthorsWu, B. / Ong, M.S. / Groessl, M. / Adhireksan, Z. / Hartinger, C.G. / Dyson, P.J. / Davey, C.A.
External linksChemistry / PubMed:21344528
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-3mnn:
A Ruthenium Antitumour Agent Forms Specific Histone Protein Adducts in the Nucleosome Core
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-MG:
Unknown entry

ChemComp-RU:
RUTHENIUM ION

ChemComp-MML:
1-methyl-4-(1-methylethyl)benzene

ChemComp-PTW:
1,3,5-triaza-7-phosphatricyclo[3.3.1.1~3,7~]decane

ChemComp-HOH:
WATER

Source
  • xenopus laevis (African clawed frog)
KeywordsSTRUCTURAL PROTEIN/DNA / NUCLEOSOME / NCP / RUTHENIUM / RAPTA-C / STRUCTURAL PROTEIN-DNA complex

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