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-Structure paper
Title | High-Resolution Structures of Trypanosoma Brucei Pteridine Reductase Ligand Complexes Inform on the Placement of New Molecular Entities in the Active Site of a Potential Drug Target |
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Journal, issue, pages | Acta Crystallogr. ,Sect. D, Vol. 66, Page 1334-, Year 2010 |
Publish date | Mar 18, 2010 (structure data deposition date) |
Authors | Dawson, A. / Tulloch, L.B. / Barrack, K.L. / Hunter, W.N. |
External links | Acta Crystallogr. ,Sect. D / PubMed:21123874 |
Methods | X-ray diffraction |
Resolution | 1.1 - 1.7 Å |
Structure data | PDB-2x9g: PDB-2x9n: PDB-2x9v: PDB-3mcv: |
Chemicals | ChemComp-NAP: ChemComp-LYA: ChemComp-ACT: ChemComp-HOH: ChemComp-AX3: ChemComp-DTD: ChemComp-NA: ChemComp-D1D: ChemComp-TMQ: ChemComp-MCV: |
Source |
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Keywords | OXIDOREDUCTASE / SHORT CHAIN DEHYDROGENASE / Pteridine reductase / antifolate |