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TitleX-ray crystal structures of monomeric and dimeric peptide inhibitors in complex with the human neonatal Fc receptor, FcRn.
Journal, issue, pagesJ. Biol. Chem., Vol. 285, Page 27694-27701, Year 2010
Publish dateMar 4, 2010 (structure data deposition date)
AuthorsMezo, A.R. / Sridhar, V. / Badger, J. / Sakorafas, P. / Nienaber, V.
External linksJ. Biol. Chem. / PubMed:20592032
MethodsX-ray diffraction
Resolution2.6 - 3.1 Å
Structure data

PDB-3m17:
Crystal structure of human FcRn with a monomeric peptide inhibitor
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-3m1b:
Crystal structure of human FcRn with a dimeric peptide inhibitor
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM/INHIBITOR / IMMUNOGLOBULIN BINDING PROTEIN / Cell membrane / Disulfide bond / Glycoprotein / IgG-binding protein / Immunoglobulin domain / Membrane / Receptor / Transmembrane / Amyloid / Amyloidosis / Disease mutation / Glycation / Immune response / MHC I / Pyrrolidone carboxylic acid / Secreted / IMMUNE SYSTEM-INHIBITOR complex / IMMUNE SYSTEM-IMMUNE SYSTEM INHIBITOR

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