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Structure paper

TitleAllosteric IGF-1R Inhibitors.
Journal, issue, pagesAcs Med. Chem. Lett., Vol. 1, Page 199-203, Year 2010
Publish dateFeb 23, 2010 (structure data deposition date)
AuthorsHeinrich, T. / Gradler, U. / Bottcher, H. / Blaukat, A. / Shutes, A.
External linksAcs Med. Chem. Lett. / PubMed:24900194
MethodsX-ray diffraction
Resolution1.79 Å
Structure data

PDB-3lw0:
IGF-1RK in complex with ligand MSC1609119A-1
Method: X-RAY DIFFRACTION / Resolution: 1.79 Å

Chemicals

ChemComp-CCX:
3-cyano-N-{1-[4-(5-cyano-1H-indol-3-yl)butyl]piperidin-4-yl}-1H-indole-7-carboxamide

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / PROTEIN KINASE

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