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Structure paper

TitleStructural basis for the allosteric control of the global transcription factor NtcA by the nitrogen starvation signal 2-oxoglutarate.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 107, Page 12487-12492, Year 2010
Publish dateJan 6, 2010 (structure data deposition date)
AuthorsZhao, M.X. / Jiang, Y.L. / He, Y.X. / Chen, Y.F. / Teng, Y.B. / Chen, Y.X. / Zhang, C.C. / Zhou, C.Z.
External linksProc. Natl. Acad. Sci. USA / PubMed:20616047
MethodsX-ray diffraction
Resolution1.9 - 2.6 Å
Structure data

PDB-3la2:
Crystal structure of NtcA in complex with 2-oxoglutarate
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-3la3:
Crystal structure of NtcA in complex with 2,2-difluoropentanedioic acid
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-3la7:
Crystal structure of NtcA in apo-form
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-AKG:
2-OXOGLUTARIC ACID

ChemComp-HOH:
WATER

ChemComp-2FT:
2,2-difluoropentanedioic acid

ChemComp-BOG:
octyl beta-D-glucopyranoside / detergent*YM

Source
  • anabaena (bacteria)
KeywordsTRANSCRIPTION / nitrogen regulator / Activator / DNA-binding / Transcription regulation

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