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-Structure paper
Title | Structural basis of membrane targeting by the Dock180 family of Rho family guanine exchange factors (Rho-GEFs). |
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Journal, issue, pages | J. Biol. Chem., Vol. 285, Page 13211-13222, Year 2010 |
Publish date | Dec 18, 2009 (structure data deposition date) |
Authors | Premkumar, L. / Bobkov, A.A. / Patel, M. / Jaroszewski, L. / Bankston, L.A. / Stec, B. / Vuori, K. / Cote, J.F. / Liddington, R.C. |
External links | J. Biol. Chem. / PubMed:20167601 |
Methods | X-ray diffraction |
Resolution | 2.37 Å |
Structure data | PDB-3l4c: |
Chemicals | ChemComp-BME: ChemComp-HOH: |
Source |
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Keywords | CELL ADHESION / CELL INVASION / APOPTOSIS / Dock180 / Dock1 / phosphoinositide specificity / Guanine Exchange Factor / Rho GTPase / cytoskeleton / cell migration / cell polarity / Cytoplasm / Guanine-nucleotide releasing factor / Membrane / Phagocytosis / Phosphoprotein / SH3 domain / SH3-binding |